Intranet

MEDIPARK - University biomedical scientific park of P.J. Safarik University

Principal investigator: Nadežda Lukáčová 
Duration of project: 10.7.2013 / 30.6.2016
Project registration number: ITMS 26220220185

Read more: Projects of EU Structural Funds

Study of the neuroprotective potential of P2X7 and CALHM1 channels in ischemia

Principal investigator: Miroslav Gottlieb
Duration of project: 20.3.2015 / 30.6.2016
Project registration number: B-MOB

The therapeutic effects of stem cells conditioned medium on the repair of the spinal cord damaged tissue: a comparative ex vivo study

Principal investigator: Lucia Slovinská
Duration of project: 1.1.2016 / 31.12.2018
Project registration number: 2/0145/16

Read more: The therapeutic effects

Investigation of postnatal neurogenesis in relation to neurodegeneration

Principal investigator: Enikö Račeková
Duration of project: 1.1.2015 / 31.12.2017
Project registration number: 2/0069/15

Read more: Investigation of postnatal neurogenesis

Neuroprotective mechanisms of the AT2 receptor stimulation after traumatic spinal cord injury

Principal investigator: Jaroslav Pavel
Duration of project: 1.1.2016 / 31.12.2018
Project registration number: 2/0160/16

 

Annotation:

There is a prolonged social as well as medical demand on intensive research, because no effective and trustworthy clinical treatment for patients with the spinal cord injury (SCI). Since most of the physiological and pathological effects of the Angiotensin II are mediated through the AT1 receptor stimulation, the AT2 receptor study was until recently at the periphery of scientific interest. At present, the AT2 receptor represents a potentially important area of investigation with possible therapeutic application since it was shown its wide neuroprotective potential. Our main objective is to contribute to the elucidation of the neuroprotective mechanisms in which the AT2 receptor plays an important role.